Evolution and Development

Élio Sucena

The Evolution and Development lab aims at exploring the interface between the fields of evolution, developmental biology and physiology with the ultimate purpose of contributing to the understanding of the rules by which this interplay shapes organisms across evolutionary time.

Currently, the research group focus on immune fucntion with the aim of dissecting its proximal and ultimate mechanisms. The research team uses an experimental approach that combines the comparative method and experimental evolution, encompassing different levels of biological organization.

Specifically, the reserach group looks at: 

  • the organismal level, using experimental evolution to study immune response evolution in Drosophila melanogaster;

  • the cellular level, by approaching immune cell function diversity and haematopoiesis, and

  • the genetic level, through the functional characterization of the genes identified with the strategies described above.