They study and quantify the role of host immune defences for controlling bacterial infections and for mitigating the ascent of drug-resistance during treatment.This research combines mathematical analysis with computer simulations, as well as tools from population dynamics, stochastic processes, and parameter inference problems, relevant to different areas of biology. The insights from mathematical models can have practical implications for biomedical settings and public health policy. This group currently collaborates with several teams in Portugal (IMM, U. Lisbon) and abroad, including France (University of Tours) and the USA (University of Tennessee, University of Michigan).