Fostering health science research in the PALOPs

In partnership with the “la Caixa” Foundation

The Calouste Gulbenkian Foundation and the “la Caixa” Foundation have been collaborating in the field of health science research in the PALOPs ever since 2015.

In late 2024, the foundations launched another joint initiative with the objective of providing incentives for the scientific communities of Angola, Cape Verde, Guinea Bissau, Mozambique and Sao Tome and Principe to undertake projects to strengthen higher education institutions in the health field, specifically research centres and units working in partnership with healthcare units, through the project “We Forward – empowering the Health Sciences in the PALOPs”. The following four project are to undergo development over the next three years. 

PROJECTS

Date

Capacity Building for the Research, Prevention and Treatment of Oncological Diseases in Albinos

A project that emerges in response to the high incidence of albinism in the provinces of Huíla and Benguela – regions characterised by their high levels of solar exposure, social vulnerabilities and high rates of oncological disease. The objective is to establish a solid and integrated infrastructure for the prevention, diagnosis and treatment of oncological diseases in albinos in conjunction with evaluating the molecular and clinical biomarkers, defining the tumoral microenvironment of skin lesions and designing a clinical-pathologic molecular model able to contribute towards better prognosis.

Location: Angola 
Promoters: Universidade Katyavala Bwila
Partners: Central Hospital of Lubango, the Portuguese Oncology Institute of Oporto and GONCOinitiative
Researcher: Madalena Chimpolo

since 2025

Initiative in Oncology

Establishing a research ecosystem integrating teaching, research and the provision of health services. This project strives to strengthen the response capacity of Guinea Bissau towards the oncological challenges currently experienced, improving the infrastructures and training specialist professionals to boost the rate of early diagnosis and expand treatment options. Among other issues, the country registers a low rate of early cancer diagnoses and with only limited treatment options due to the overall lack of infrastructures and specialist professionals.

Location: Guinea Bissau
Promoter: Jean Piaget de Bissau University
Researcher: Bubacar Embaló

since 2025

Relationship between tuberculosis and diabetes mellitus

This project seeks to grasp the relationship between tuberculosis and diabetes mellitus, one of the chronic non-transmissible diseases that are emerging as a growing problem in Sub-Saharan Africa, coexisting with high rates of infectious diseases, such as tuberculosis. This project sets out to undertake a prospective study in two groups of patients previously identified as bearers of latent infection by tuberculosis and diabetes mellitus, with the objective of deciphering the bidirectional relationship between the two conditions, thus evaluating the impact of diabetes on the development and progression of tuberculosis as well as the effect of tuberculosis on glycemic control.

Location: Guinea Bissau
Promoter: Lusófona University
Researcher: Baltazar Cá

since 2025

Strengthening the capabilities of Pediatric Research Centres

This project aims to strengthen the capabilities of Pediatric Research Centres that are engaged in cutting-edge research in pediatrics, especially as regards the preparation of clinical trials for new drugs and vaccines in collaboration with external institutions and with EDCTP financing. Thus, this project sets out to establish the infrastructural and technological conditions and strengthen the human resources of the Microbiology Laboratory at the Eduardo Mondlane University. The training is focused on best clinical and laboratory practices, managing clinical trials and on bioethical questions.

Location: Moçambique
Promoter: Faculty of Medicine, the Eduardo Mondlane University
Researcher: José Sumbana

since 2025

Strengthening health research in the PALOP countries

Since 2015, the Calouste Gulbenkian Foundation and the “la Caixa” Foundation have been collaborating on health research in the PALOP countries. By the end of 2022, they had signed a collaboration protocol with the aim of developing a programme to encourage the countries’ scientific communities to carry out research projects that contribute to improving healthcare provision.

This is how the We’Search programme was born, a call to strengthen scientific institutions through clinical research projects in Portuguese-speaking African countries (PALOP), and which supports the participation of researchers in international congresses.

Support for clinical research projects in the PALOP countries

PROJECTS

Date

CV-POC – Cape Verde Personalized Oncology Care

Upgrading of equipment and implementation of advanced techniques in the recent Molecular Biology Laboratory of the Agostinho Neto University Hospital, such as genetic testing, to support and guide therapeutic decisions, personalised treatment and monitoring in Cape Verdean cancer patients.

Location: Cape Verde
Promoter:  Dr. Agostinho Neto University Hospital
Researcher: Pamela Borges

since 2024

Malango II – Triple Artemisinin Combination Therapy for stopping malaria resistance

New treatment strategy against malaria, one of the diseases with the highest mortality rate in Africa.

Location: Angola
Promoter: National Institute for Health Research in Angola/CISA 
Researcher: Elsa Fortes Gabriel

since 2024

Respira-CV – Airway colonization and microbiome in relation to asthma and atopy in children from Cabo Verde

Strengthening knowledge, prevention, diagnosis and treatment of respiratory diseases (such as asthma or allergic rhinitis) in Cape Verdean children.

Location: Cape Verde
Promoter: University of Cape Verde
Researcher: Isabel Inês Araújo

since 2024

MAMAEXPERT – Use of GeneXpert® STRAT4 assay for evaluation of breast cancer biomarkers in cytology in Mozambique

Search for alternative methods of diagnosis and treatment of breast cancer in places with few resources, through testing with the GeneXpert system, which is more widely accessible in African hospitals.

Location: Mozambique
Promoter: Eduardo Mondlane University
Researcher: Carla Carrilho

since 2024

LEARNER – A Prospective, Randomized Controlled Study to Evaluate the Effects of Daily Low Dose Aspirin in Pregnant women with Sickle Disease Cell

Monitoring and treatment of Sickle Cell Disease in pregnant women, with the aim of contributing to the reduction of maternal and infant mortality in the country.

Location: Angola
Promoter: National Institute for Health Research in Angola/CISA
Researcher: Joana Morais

since 2024

Grants for attending congresses

Following an open call for applications, 7 grants were awarded to PALOP researchers – graduates of the Science Management courses and/or leaders of research projects funded by both foundations – to take part in international congresses in 2024.

Other projects receiving support

In the context of a call for applications launched in 2021 to support health research projects aimed at scientific institutions in the PALOP countries, whose researchers took part in the three editions of the Science Management course, organised as part of a partnership between the FCG and the “la Caixa” Foundation.

PROJECTS

Date

INTEGRATE – Helminth infections and allergic respiratory diseases. Does a neglected tropical disease influence a non-communicable disease?

Location: Angola
Promoter: National Institute for Health Research in Angola/CISA

since 2022

Kids-CoV – Epidemiology and characteristics of SARS-CoV-2 infection among children and their households in Mozambique

Location: Mozambique
Promoter: National Institute of Health in Mozambique

since 2022

INCUBATOR – Clinical-Pathological Characterization of PALOP`S Cancer

Location: Cape Verde
Promoter: University of Cape Verde

since 2022

 

 

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