Evolution and Development
The Evolution and Development lab aims at exploring the interface between the fields of evolution and developmental biology with the ultimate purpose of contributing to the understanding of the rules by which this interplay shapes organisms across evolutionary time.
In particular, research carried out in the lab focuses on evolutionary novelties, that is, new traits (either morphological, physiological or behavioural) that may participate in the emergence of adaptive radiations into novel niches.
The research group approach this concept experimentally at different levels of biological organization and through both the comparative method and experimental evolution. Specifically, they look into novelty at:
- the genetic level, studying gene expression evolution upon gene duplication,
- the cellular level, approaching immune cell function diversity and hematopoiesis in Drosophila;
- the organismal level, by studying the evolution of the immune response in arthropods using Drosophila melanogaster as a reference model.
- Immune cell function diversity and haematopoiesis in Drosophila
- Evolution of immune response in Drosophila melanogaster
- Faria, V. G., Martins, N. E., Magalhães, S., Paulo, T. F., Nolte, V., Schlötterer, C., Sucena, É., Teixeira, L. (2016) Drosophila Adaptation to Viral Infection through Defensive Symbiont Evolution PLoS Genetics 12(9) : e1006297
- Leitão, A.B., Sucena, É. (2015) Drosophila sessile hemocyte clusters are true hematopoietic tissues that regulate larval blood cell differentiation eLife 4 : e06166
- Faria, V.G., Martins, N.E., Paulo, T.F., Teixeira, L., Sucena, É., Magalhães, S. (2015) Evolution of Drosophila resistance against different pathogens and infection routes entails no detectable maintenance costs Evolution 69(11) : 2799–2809
- Tanaka, K., Diekmann, Y., Hazbun, A., Hijazi, A., Vreede, B., Roch, F., Sucena, É.(2015) Multi-species analysis of expression pattern diversification in the recently expanded insect Ly6 gene family Molecular Biology and Evolution 32(7) : 1730-1747
- Fauré, A., Vreede, B.M.I., Sucena, É., Chaouiya, C. (2014) A Discrete Model of Drosophila Eggshell Patterning Reveals Cell-Autonomous and Juxtacrine Effects PLoS Comput Biol 10(3) : e1003527
- Martins, N.E., Faria, V.G., Nolte, V., Schlötterer, C., Teixeira, L., Sucena, É., Magalhães, S. (2014) Host adaptation to viruses relies on few genes with different cross-resistance properties Proc. Natl Acad Sci USA 111(16) : 5938-43
- Sucena,. É., Vanderberghe, K., Zhurov, V., Grbic, M. (2014) Reversion of developmental mode in insects: evolution from long germband to short germband in the polyembrionic wasp Macrocentrus cingulum Brischke Evolution and Development 16(4) : 233–246
- Martins, N.E., Faria, V.G., Teixeira, L., Magalhães, S., Sucena, É. (2013) Host adaptation is contingent upon the infection route taken by pathogens PLOS Pathogens 9(9) : e1003601
- Vreede, B.M.I.., Lynch, J.A., Roth, S., Sucena, É. (2013) Co-option of a coordinate system defined by the EGFr and Dpp pathways in the evolution of a morphological novelty Evo Devo 4 (1) : 7
- Sucena, É and Stern, DL (2000) Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby Proc Natl Acad Sci U S A 97(9) : 4530-4
- 16 jan 2020
- 25 sep 2019
Élio Sucena, Principal Investigator
PhD in Biology, University of Cambridge, United Kingdom
Phone: +351 214 464 639